HCN4 (NM_005477) Human Tagged ORF Clone Lentiviral Particle

SKU RC216770L4V

Lenti ORF particles, HCN4 (mGFP-tagged)-Human hyperpolarization activated cyclic nucleotide-gated potassium channel 4 (HCN4), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: HCN4
• Synonyms: SSS2
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC216770).
• ACCN: NM_005477
• ORF Size: 3609 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_005477.1
• RefSeq Size: 5065 bp
• RefSeq ORF: 3612 bp
• Locus ID: 10021
• UniProt ID: Q9Y3Q4
• Cytogenetics: 15q24.1
• Domains: cNMP, ion_trans
• Protein Families: Druggable Genome, Ion Channels: Cyclic nucleotide gated, Transmembrane
• MW: 128.9 kDa
• Summary: This gene encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in this gene have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15. [provided by RefSeq, Oct 2008]