RAG1 (NM_000448) Human Tagged ORF Clone Lentiviral Particle
SKU
RC216503L2V
Lenti ORF particles, RAG1 (mGFP-tagged) - Human recombination activating gene 1 (RAG1), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | RAG1 |
Synonyms | RAG-1; RNF74 |
Vector | pLenti-C-mGFP |
Mammalian Cell Selection | None |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC216503).
|
ACCN | NM_000448 |
ORF Size | 3129 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_000448.1, NP_000439.1 |
RefSeq Size | 6557 bp |
RefSeq ORF | 3132 bp |
Locus ID | 5896 |
UniProt ID | P15918 |
Cytogenetics | 11p12 |
Protein Families | Druggable Genome |
Protein Pathways | Primary immunodeficiency |
MW | 118.9 kDa |
Summary | The protein encoded by this gene is involved in activation of immunoglobulin V-D-J recombination. The encoded protein is involved in recognition of the DNA substrate, but stable binding and cleavage activity also requires RAG2. Defects in this gene can be the cause of several diseases. [provided by RefSeq, Jul 2008] |
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