ADAMTS10 (NM_030957) Human Tagged ORF Clone Lentiviral Particle

SKU RC215901L4V

Lenti ORF particles, ADAMTS10 (mGFP-tagged) - Human ADAM metallopeptidase with thrombospondin type 1 motif, 10 (ADAMTS10), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: ADAMTS10
• Synonyms: ADAM-TS10; ADAMTS-10; WMS; WMS1
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC215901).
• ACCN: NM_030957
• ORF Size: 3309 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_030957.2
• RefSeq Size: 4237 bp
• RefSeq ORF: 3312 bp
• Locus ID: 81794
• UniProt ID: Q9H324
• Cytogenetics: 19p13.2
• Domains: Pep_M12B_propep, Reprolysin, tsp_1
• Protein Families: Druggable Genome, Secreted Protein
• MW: 120.7 kDa
• Summary: This gene belongs to the ADAMTS (a disintegrin and metalloproteinase domain with thrombospondin type-1 motifs) family of zinc-dependent proteases. ADAMTS proteases are complex secreted enzymes containing a prometalloprotease domain of the reprolysin type attached to an ancillary domain with a highly conserved structure that includes at least one thrombospondin type 1 repeat. They have been demonstrated to have important roles in connective tissue organization, coagulation, inflammation, arthritis, angiogenesis and cell migration. The product of this gene plays a major role in growth and in skin, lens, and heart development. It is also a candidate gene for autosomal recessive Weill-Marchesani syndrome. [provided by RefSeq, Jul 2008]