Smad Interacting Protein 1 (ZEB2) (NM_014795) Human Tagged ORF Clone Lentiviral Particle

SKU RC215227L4V

Lenti ORF particles, ZEB2 (mGFP-tagged)-Human zinc finger E-box binding homeobox 2 (ZEB2), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Smad Interacting Protein 1
• Synonyms: HSPC082; SIP-1; SIP1; SMADIP1; ZFHX1B
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC215227).
• ACCN: NM_014795
• ORF Size: 3642 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_014795.2
• RefSeq Size: 9243 bp
• RefSeq ORF: 3645 bp
• Locus ID: 9839
• UniProt ID: O60315
• Cytogenetics: 2q22.3
• Domains: homeobox, zf-C2H2
• Protein Families: Druggable Genome, Transcription Factors
• MW: 136.4 kDa
• Summary: The protein encoded by this gene is a member of the Zfh1 family of 2-handed zinc finger/homeodomain proteins. It is located in the nucleus and functions as a DNA-binding transcriptional repressor that interacts with activated SMADs. Mutations in this gene are associated with Hirschsprung disease/Mowat-Wilson syndrome. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Jan 2010]