KDM5B (NM_006618) Human Tagged ORF Clone Lentiviral Particle

SKU RC214918L4V

Lenti ORF particles, KDM5B (mGFP-tagged) - Human lysine (K)-specific demethylase 5B (KDM5B), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: KDM5B
• Synonyms: CT31; JARID1B; MRT65; PLU-1; PLU1; PPP1R98; PUT1; RBBP2H1A; RBP2-H1
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214918).
• ACCN: NM_006618
• ORF Size: 4632 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_006618.3
• RefSeq Size: 6393 bp
• RefSeq ORF: 4635 bp
• Locus ID: 10765
• UniProt ID: Q9UGL1
• Cytogenetics: 1q32.1
• Domains: ARID, JmjC, JmjN, PHD, zf-C5HC2
• Protein Families: Druggable Genome, Transcription Factors
• MW: 175.5 kDa
• Summary: This gene encodes a lysine-specific histone demethylase that belongs to the jumonji/ARID domain-containing family of histone demethylases. The encoded protein is capable of demethylating tri-, di- and monomethylated lysine 4 of histone H3. This protein plays a role in the transcriptional repression or certain tumor suppressor genes and is upregulated in certain cancer cells. This protein may also play a role in genome stability and DNA repair. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Nov 2016]