PIK3AP1 (NM_152309) Human Tagged ORF Clone Lentiviral Particle

SKU RC214125L4V

Lenti ORF particles, PIK3AP1 (mGFP-tagged) - Human phosphoinositide-3-kinase adaptor protein 1 (PIK3AP1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: PIK3AP1
• Synonyms: BCAP
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214125).
• ACCN: NM_152309
• ORF Size: 2415 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_152309.2, NP_689522.2
• RefSeq Size: 4817 bp
• RefSeq ORF: 2418 bp
• Locus ID: 118788
• UniProt ID: Q6ZUJ8
• Cytogenetics: 10q24.1
• Protein Families: Druggable Genome
• Protein Pathways: B cell receptor signaling pathway
• MW: 90.2 kDa
• Summary: Signaling adapter that contributes to B-cell development by linking B-cell receptor (BCR) signaling to the phosphoinositide 3-kinase (PI3K)-Akt signaling pathway. Has a complementary role to the BCR coreceptor CD19, coupling BCR and PI3K activation by providing a docking site for the PI3K subunit PIK3R1. Alternatively, links Toll-like receptor (TLR) signaling to PI3K activation, a process preventing excessive inflammatory cytokine production. Also involved in the activation of PI3K in natural killer cells. May be involved in the survival of mature B-cells via activation of REL.[UniProtKB/Swiss-Prot Function]