15 Lipoxygenase 2 (ALOX15B) (NM_001039131) Human Tagged ORF Clone Lentiviral Particle

SKU
RC214075L4V
Lenti ORF particles, ALOX15B (mGFP-tagged)-Human arachidonate 15-lipoxygenase, type B (ALOX15B), transcript variant b, 200ul, >10^7 TU/mL
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$1,110.00
5 Weeks*
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol 15 Lipoxygenase 2
Synonyms 15-LOX-2
Vector pLenti-C-mGFP-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC214075).
ACCN NM_001039131
ORF Size 1806 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_001039131.1
RefSeq Size 2508 bp
RefSeq ORF 1809 bp
Locus ID 247
UniProt ID O15296
Cytogenetics 17p13.1
Protein Families Druggable Genome
Protein Pathways Arachidonic acid metabolism, Metabolic pathways
MW 67.2 kDa
Summary This gene encodes a member of the lipoxygenase family of structurally related nonheme iron dioxygenases involved in the production of fatty acid hydroperoxides. The encoded protein converts arachidonic acid exclusively to 15S-hydroperoxyeicosatetraenoic acid, while metabolizing linoleic acid less effectively. This gene is located in a cluster of related genes and a pseudogene that spans approximately 100 kilobases on the short arm of chromosome 17. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jul 2008]
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