BACH2 (NM_021813) Human Tagged ORF Clone Lentiviral Particle

SKU RC214061L2V

Lenti ORF particles, BACH2 (mGFP-tagged) - Human BTB and CNC homology 1, basic leucine zipper transcription factor 2 (BACH2), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: BACH2
• Synonyms: BTBD25; IMD60
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC214061).
• ACCN: NM_021813
• ORF Size: 2523 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_021813.1, NP_068585.1
• RefSeq Size: 9120 bp
• RefSeq ORF: 2526 bp
• Locus ID: 60468
• UniProt ID: Q9BYV9
• Cytogenetics: 6q15
• Domains: BRLZ, BTB
• Protein Families: Druggable Genome, Transcription Factors
• MW: 92.4 kDa
• Summary: Transcriptional regulator that acts as repressor or activator (By similarity). Binds to Maf recognition elements (MARE) (By similarity). Plays an important role in coordinating transcription activation and repression by MAFK (By similarity). Induces apoptosis in response to oxidative stress through repression of the antiapoptotic factor HMOX1 (PubMed:17018862). Positively regulates the nuclear import of actin (By similarity).[UniProtKB/Swiss-Prot Function]