GUCY2C (NM_004963) Human Tagged ORF Clone Lentiviral Particle

SKU RC213901L4V

Lenti ORF particles, GUCY2C (mGFP-tagged) - Human guanylate cyclase 2C (heat stable enterotoxin receptor) (GUCY2C), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: GUCY2C
• Synonyms: DIAR6; GC-C; GUC2C; MECIL; MUCIL; STAR
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC213901).
• ACCN: NM_004963
• ORF Size: 3219 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_004963.1
• RefSeq Size: 3745 bp
• RefSeq ORF: 3222 bp
• Locus ID: 2984
• UniProt ID: P25092
• Cytogenetics: 12p12.3
• Protein Families: Druggable Genome, Protein Kinase, Transmembrane
• Protein Pathways: Purine metabolism
• MW: 123.2 kDa
• Summary: This gene encodes a transmembrane protein that functions as a receptor for endogenous peptides guanylin and uroguanylin, and the heat-stable E. coli enterotoxin. The encoded protein activates the cystic fibrosis transmembrane conductance regulator. Mutations in this gene are associated with familial diarrhea (autosomal dominant) and meconium ileus (autosomal recessive). [provided by RefSeq, Nov 2016]