NHLRC1 (NM_198586) Human Tagged ORF Clone Lentiviral Particle

SKU RC213526L4V

Lenti ORF particles, NHLRC1 (mGFP-tagged) - Human NHL repeat containing 1 (NHLRC1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: NHLRC1
• Synonyms: bA204B7.2; EPM2A; EPM2B; MALIN
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC213526).
• ACCN: NM_198586
• ORF Size: 1185 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_198586.2
• RefSeq Size: 2134 bp
• RefSeq ORF: 1188 bp
• Locus ID: 378884
• UniProt ID: Q6VVB1
• Cytogenetics: 6p22.3
• Protein Pathways: Ubiquitin mediated proteolysis
• MW: 42.3 kDa
• Summary: The protein encoded by this gene is a single subunit E3 ubiquitin ligase. Laforin is polyubiquitinated by the encoded protein. Defects in this intronless gene lead to an accumulation of laforin and onset of Lafora disease, also known as progressive myoclonic epilepsy type 2 (EPM2).[provided by RefSeq, Mar 2010]