Sodium Iodide Symporter (SLC5A5) (NM_000453) Human Tagged ORF Clone Lentiviral Particle

SKU RC211244L2V

Lenti ORF particles, SLC5A5 (mGFP-tagged) - Human solute carrier family 5 (sodium iodide symporter), member 5 (SLC5A5), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Sodium Iodide Symporter
• Synonyms: NIS; TDH1
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC211244).
• ACCN: NM_000453
• ORF Size: 1929 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000453.1
• RefSeq Size: 3594 bp
• RefSeq ORF: 1932 bp
• Locus ID: 6528
• UniProt ID: Q92911
• Cytogenetics: 19p13.11
• Protein Families: Druggable Genome, Transmembrane
• MW: 68.7 kDa
• Summary: This gene encodes a member of the sodium glucose cotransporter family. The encoded protein is responsible for the uptake of iodine in tissues such as the thyroid and lactating breast tissue. The iodine taken up by the thyroid is incorporated into the metabolic regulators triiodothyronine (T3) and tetraiodothyronine (T4). Mutations in this gene are associated with thyroid dyshormonogenesis 1.[provided by RefSeq, Sep 2009]