VEPH1 (NM_024621) Human Tagged ORF Clone Lentiviral Particle

SKU RC210974L4V

Lenti ORF particles, VEPH1 (mGFP-tagged) - Human ventricular zone expressed PH domain homolog 1 (zebrafish) (VEPH1), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: VEPH1
• Synonyms: MELT; VEPH
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC210974).
• ACCN: NM_024621
• ORF Size: 2499 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_024621.1
• RefSeq Size: 4313 bp
• RefSeq ORF: 2502 bp
• Locus ID: 79674
• UniProt ID: Q14D04
• Cytogenetics: 3q25.31-q25.32
• Domains: PH
• MW: 94.8 kDa
• Summary: Interacts with TGF-beta receptor type-1 (TGFBR1) and inhibits dissociation of activated SMAD2 from TGFBR1, impeding its nuclear accumulation and resulting in impaired TGF-beta signaling. May also affect FOXO, Hippo and Wnt signaling.[UniProtKB/Swiss-Prot Function]