LRP15 (LRRC3B) (NM_052953) Human Tagged ORF Clone Lentiviral Particle

SKU RC209766L4V

Lenti ORF particles, LRRC3B (mGFP-tagged) - Human leucine rich repeat containing 3B (LRRC3B), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: LRP15
• Synonyms: LRP15
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC209766).
• ACCN: NM_052953
• ORF Size: 777 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_052953.2
• RefSeq Size: 1718 bp
• RefSeq ORF: 780 bp
• Locus ID: 116135
• UniProt ID: Q96PB8
• Cytogenetics: 3p24.1
• Domains: LRR, LRRNT, LRR_TYP
• Protein Families: Transmembrane
• MW: 29.3 kDa
• Summary: The protein encoded by this gene is a tumor suppressor, with lowered expression levels found in gastric, renal, colorectal, lung, and breast cancer tissues. The promoter of this gene is frequently hypermethylated in these cancer tissues, although the hypermethylation does not appear to be the cause of the reduced expression of this gene. Several transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Dec 2015]