MLYCD (NM_012213) Human Tagged ORF Clone Lentiviral Particle
SKU
RC208587L4V
Lenti ORF particles, MLYCD (mGFP-tagged) - Human malonyl-CoA decarboxylase (MLYCD), nuclear gene encoding mitochondrial protein, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | MLYCD |
Synonyms | MCD |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC208587).
|
ACCN | NM_012213 |
ORF Size | 1479 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_012213.2 |
RefSeq Size | 2211 bp |
RefSeq ORF | 1482 bp |
Locus ID | 23417 |
UniProt ID | O95822 |
Cytogenetics | 16q23.3 |
Domains | MCD |
Protein Families | Druggable Genome |
Protein Pathways | beta-Alanine metabolism, Metabolic pathways, Propanoate metabolism |
MW | 54.8 kDa |
Summary | The product of this gene catalyzes the breakdown of malonyl-CoA to acetyl-CoA and carbon dioxide. Malonyl-CoA is an intermediate in fatty acid biosynthesis, and also inhibits the transport of fatty acyl CoAs into mitochondria. Consequently, the encoded protein acts to increase the rate of fatty acid oxidation. It is found in mitochondria, peroxisomes, and the cytoplasm. Mutations in this gene result in malonyl-CoA decarboyxlase deficiency. [provided by RefSeq, Jul 2008] |
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