RAD21 (NM_006265) Human Tagged ORF Clone Lentiviral Particle

SKU RC208262L2V

Lenti ORF particles, RAD21 (mGFP-tagged) - Human RAD21 homolog (S. pombe) (RAD21), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: RAD21
• Synonyms: CDLS4; hHR21; HR21; HRAD21; MCD1; MGS; NXP1; SCC1
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC208262).
• ACCN: NM_006265
• ORF Size: 1893 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_006265.1
• RefSeq Size: 3773 bp
• RefSeq ORF: 1896 bp
• Locus ID: 5885
• UniProt ID: O60216
• Cytogenetics: 8q24.11
• Domains: Rad21_Rec8, Rad21_Rec8_N
• Protein Families: Druggable Genome
• Protein Pathways: Cell cycle
• MW: 71.7 kDa
• Summary: The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad21, a gene involved in the repair of DNA double-strand breaks, as well as in chromatid cohesion during mitosis. This protein is a nuclear phospho-protein, which becomes hyperphosphorylated in cell cycle M phase. The highly regulated association of this protein with mitotic chromatin specifically at the centromere region suggests its role in sister chromatid cohesion in mitotic cells. [provided by RefSeq, Jul 2008]