Brk (PTK6) (NM_005975) Human Tagged ORF Clone Lentiviral Particle

SKU RC207766L4V

Lenti ORF particles, PTK6 (mGFP-tagged) - Human PTK6 protein tyrosine kinase 6 (PTK6), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Brk
• Synonyms: BRK
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207766).
• ACCN: NM_005975
• ORF Size: 1353 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_005975.2
• RefSeq Size: 2519 bp
• RefSeq ORF: 1356 bp
• Locus ID: 5753
• UniProt ID: Q13882
• Cytogenetics: 20q13.33
• Protein Families: Druggable Genome, Protein Kinase, Secreted Protein
• MW: 51.7 kDa
• Summary: The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2012]