KLF15 (NM_014079) Human Tagged ORF Clone Lentiviral Particle
SKU
RC207523L4V
Lenti ORF particles, KLF15 (mGFP-tagged) - Human Kruppel-like factor 15 (KLF15), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | KLF15 |
Synonyms | KKLF |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC207523).
|
ACCN | NM_014079 |
ORF Size | 1248 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_014079.2 |
RefSeq Size | 2539 bp |
RefSeq ORF | 1251 bp |
Locus ID | 28999 |
UniProt ID | Q9UIH9 |
Cytogenetics | 3q21.3 |
Protein Families | Transcription Factors |
MW | 44 kDa |
Summary | Transcriptional regulator that binds to the GA element of the CLCNKA promoter. Binds to the KCNIP2 promoter and regulates KCNIP2 circadian expression in the heart (By similarity). Is a repressor of CCN2 expression, involved in the control of cardiac fibrosis. It is also involved in the control of cardiac hypertrophy acting through the inhibition of MEF2A and GATA4 (By similarity). Involved in podocyte differentiation (By similarity). Inhibits MYOCD activity. Is a negative regulator of TP53 acetylation. Inhibits NF-kappa-B activation through repression of EP300-dependent RELA acetylation.[UniProtKB/Swiss-Prot Function] |
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