FNDC4 (NM_022823) Human Tagged ORF Clone Lentiviral Particle

SKU RC207471L4V

Lenti ORF particles, FNDC4 (mGFP-tagged) - Human fibronectin type III domain containing 4 (FNDC4), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: FNDC4
• Synonyms: FRCP1
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207471).
• ACCN: NM_022823
• ORF Size: 702 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_022823.1
• RefSeq Size: 1697 bp
• RefSeq ORF: 705 bp
• Locus ID: 64838
• UniProt ID: Q9H6D8
• Cytogenetics: 2p23.3
• Domains: FN3
• Protein Families: Transmembrane
• MW: 25.2 kDa
• Summary: Acts as an anti-inflammatory factor in the intestine and colon. Binds to and acts on macrophages to downregulate pro-inflammatory gene expression. Affects key macrophage functions, including phagocytosis, by downregulating many key pathways for macrophage activation, partly via by STAT3 activation and signaling. May be required to dampen the immunological response in colitis.[UniProtKB/Swiss-Prot Function]