TRIM22 (NM_006074) Human Tagged ORF Clone Lentiviral Particle

SKU RC207431L4V

Lenti ORF particles, TRIM22 (mGFP-tagged) - Human tripartite motif containing 22 (TRIM22), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: TRIM22
• Synonyms: GPSTAF50; RNF94; STAF50
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC207431).
• ACCN: NM_006074
• ORF Size: 1494 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_006074.3
• RefSeq Size: 3111 bp
• RefSeq ORF: 1497 bp
• Locus ID: 10346
• UniProt ID: Q8IYM9
• Cytogenetics: 11p15.4
• Domains: RING, zf-B_box
• Protein Families: Druggable Genome, Transcription Factors
• MW: 56.9 kDa
• Summary: The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to the cytoplasm and its expression is induced by interferon. The protein down-regulates transcription from the HIV-1 LTR promoter region, suggesting that function of this protein may be to mediate interferon's antiviral effects. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2010]