Bax inhibitor 1 (TMBIM6) (NM_003217) Human Tagged ORF Clone Lentiviral Particle

SKU RC206916L2V

Lenti ORF particles, TMBIM6 (mGFP-tagged) - Human transmembrane BAX inhibitor motif containing 6 (TMBIM6), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Bax inhibitor 1
• Synonyms: BAXI1; BI-1; TEGT
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206916).
• ACCN: NM_003217
• ORF Size: 711 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_003217.1
• RefSeq Size: 2600 bp
• RefSeq ORF: 714 bp
• Locus ID: 7009
• UniProt ID: P55061
• Cytogenetics: 12q13.12
• Domains: UPF0005
• Protein Families: Druggable Genome, Transmembrane
• MW: 26.4 kDa
• Summary: Suppressor of apoptosis (PubMed:21075086). Modulates unfolded protein response signaling (PubMed:21075086). Modulates ER calcium homeostasis by acting as a calcium-leak channel (PubMed:22128171). Negatively regulates autophagy and autophagosome formation, especially during periods of nutrient deprivation, and reduces cell survival during starvation (By similarity).[UniProtKB/Swiss-Prot Function]