Islet 1 (ISL1) (NM_002202) Human Tagged ORF Clone Lentiviral Particle

SKU RC206893L4V

Lenti ORF particles, ISL1 (mGFP-tagged) - Human ISL LIM homeobox 1 (ISL1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Islet 1
• Synonyms: Isl-1; ISLET1
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206893).
• ACCN: NM_002202
• ORF Size: 1047 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_002202.2, NP_002193.2
• RefSeq Size: 2729 bp
• RefSeq ORF: 1050 bp
• Locus ID: 3670
• UniProt ID: P61371
• Cytogenetics: 5q11.1
• Protein Families: ES Cell Differentiation/IPS, Transcription Factors
• MW: 39 kDa
• Summary: This gene encodes a member of the LIM/homeodomain family of transcription factors. The encoded protein binds to the enhancer region of the insulin gene, among others, and may play an important role in regulating insulin gene expression. The encoded protein is central to the development of pancreatic cell lineages and may also be required for motor neuron generation. Mutations in this gene have been associated with maturity-onset diabetes of the young. [provided by RefSeq, Jul 2008]