SIGLEC5 (NM_003830) Human Tagged ORF Clone Lentiviral Particle

SKU RC206610L4V

Lenti ORF particles, SIGLEC5 (mGFP-tagged) - Human sialic acid binding Ig-like lectin 5 (SIGLEC5), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: SIGLEC5
• Synonyms: CD33L2; CD170; OB-BP2; OBBP2; SIGLEC-5
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206610).
• ACCN: NM_003830
• ORF Size: 1653 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_003830.1
• RefSeq Size: 2523 bp
• RefSeq ORF: 1656 bp
• Locus ID: 8778
• UniProt ID: O15389
• Cytogenetics: 19q13.41
• Domains: ig
• Protein Families: Druggable Genome, Transmembrane
• MW: 60.7 kDa
• Summary: This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. [provided by RefSeq, Feb 2012]