Myocilin (MYOC) (NM_000261) Human Tagged ORF Clone Lentiviral Particle

SKU RC206556L4V

Lenti ORF particles, MYOC (mGFP-tagged) - Human myocilin, trabecular meshwork inducible glucocorticoid response (MYOC), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Myocilin
• Synonyms: GLC1A; GPOA; JOAG; JOAG1; TIGR
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206556).
• ACCN: NM_000261
• ORF Size: 1512 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000261.1
• RefSeq Size: 2061 bp
• RefSeq ORF: 1515 bp
• Locus ID: 4653
• UniProt ID: Q99972
• Cytogenetics: 1q24.3
• Protein Families: Druggable Genome, Secreted Protein
• MW: 56.8 kDa
• Summary: MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma. [provided by RefSeq, Jul 2008]