Glycerol 3 Phosphate Dehydrogenase (GPD1) (NM_005276) Human Tagged ORF Clone Lentiviral Particle

SKU
RC206538L4V
Lenti ORF particles, GPD1 (mGFP-tagged) - Human glycerol-3-phosphate dehydrogenase 1 (soluble) (GPD1), 200ul, >10^7 TU/mL
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    Expression-ready ORF plasmid in lenti backbone

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$1,007.00
5 Weeks*
Specifications
Product Data
Type Human Tagged ORF Clone Lentiviral Particle
Tag mGFP
Target Symbol Glycerol 3 Phosphate Dehydrogenase
Synonyms GPD-C; GPDH-C; HTGTI
Vector pLenti-C-mGFP-P2A-Puro
Mammalian Cell Selection Puromycin
Sequence Data
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC206538).
ACCN NM_005276
ORF Size 1047 bp
OTI Disclaimer The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
OTI Annotation This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
Shipping Dry Ice
Reference Data
RefSeq NM_005276.2
RefSeq Size 3083 bp
RefSeq ORF 1050 bp
Locus ID 2819
UniProt ID P21695
Cytogenetics 12q13.12
Protein Pathways Glycerophospholipid metabolism
MW 37.6 kDa
Summary This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012]
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