Glycerol 3 Phosphate Dehydrogenase (GPD1) (NM_005276) Human Tagged ORF Clone Lentiviral Particle
SKU
RC206538L4V
Lenti ORF particles, GPD1 (mGFP-tagged) - Human glycerol-3-phosphate dehydrogenase 1 (soluble) (GPD1), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | Glycerol 3 Phosphate Dehydrogenase |
Synonyms | GPD-C; GPDH-C; HTGTI |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC206538).
|
ACCN | NM_005276 |
ORF Size | 1047 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_005276.2 |
RefSeq Size | 3083 bp |
RefSeq ORF | 1050 bp |
Locus ID | 2819 |
UniProt ID | P21695 |
Cytogenetics | 12q13.12 |
Protein Pathways | Glycerophospholipid metabolism |
MW | 37.6 kDa |
Summary | This gene encodes a member of the NAD-dependent glycerol-3-phosphate dehydrogenase family. The encoded protein plays a critical role in carbohydrate and lipid metabolism by catalyzing the reversible conversion of dihydroxyacetone phosphate (DHAP) and reduced nicotine adenine dinucleotide (NADH) to glycerol-3-phosphate (G3P) and NAD+. The encoded cytosolic protein and mitochondrial glycerol-3-phosphate dehydrogenase also form a glycerol phosphate shuttle that facilitates the transfer of reducing equivalents from the cytosol to mitochondria. Mutations in this gene are a cause of transient infantile hypertriglyceridemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Mar 2012] |
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