GABA A Receptor alpha 3 (GABRA3) (NM_000808) Human Tagged ORF Clone Lentiviral Particle
SKU
RC206286L4V
Lenti ORF particles, GABRA3 (mGFP-tagged)-Human gamma-aminobutyric acid (GABA) A receptor, alpha 3 (GABRA3), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | GABA A Receptor alpha 3 |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC206286).
|
ACCN | NM_000808 |
ORF Size | 1476 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_000808.2 |
RefSeq Size | 1901 bp |
RefSeq ORF | 1479 bp |
Locus ID | 2556 |
UniProt ID | P34903 |
Cytogenetics | Xq28 |
Domains | Neur_chan_LBD, Neur_chan_memb |
Protein Families | Druggable Genome, Ion Channels: Cys-loop Receptors, Transmembrane |
Protein Pathways | Neuroactive ligand-receptor interaction |
MW | 55 kDa |
Summary | GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. [provided by RefSeq, Jul 2008] |
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