Signal peptide peptidase like 2B (SPPL2B) (NM_001077238) Human Tagged ORF Clone Lentiviral Particle

SKU RC206134L4V

Lenti ORF particles, SPPL2B (mGFP-tagged)-Human signal peptide peptidase-like 2B (SPPL2B), transcript variant 3, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Signal peptide peptidase like 2B
• Synonyms: IMP-4; IMP4; PSH4; PSL1
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206134).
• ACCN: NM_001077238
• ORF Size: 1533 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001077238.1
• RefSeq Size: 3832 bp
• RefSeq ORF: 1536 bp
• Locus ID: 56928
• UniProt ID: Q8TCT7
• Cytogenetics: 19p13.3
• Protein Families: Protease, Transmembrane
• MW: 56.4 kDa
• Summary: This gene encodes a member of the GXGD family of aspartic proteases. The GXGD proteases are transmembrane proteins with two conserved catalytic motifs localized within the membrane-spanning regions. This enzyme localizes to endosomes, lysosomes, and the plasma membrane. It cleaves the transmembrane domain of tumor necrosis factor alpha to release the intracellular domain, which triggers cytokine expression in the innate and adaptive immunity pathways. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]