TROVE2 (RO60) (NM_001042370) Human Tagged ORF Clone Lentiviral Particle

SKU RC206071L4V

Lenti ORF particles, TROVE2 (mGFP-tagged) - Human TROVE domain family, member 2 (TROVE2), transcript variant 3, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: RO60
• Synonyms: RORNP; SSA2; TROVE2
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC206071).
• ACCN: NM_001042370
• ORF Size: 1614 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001042370.1
• RefSeq Size: 2091 bp
• RefSeq ORF: 1605 bp
• Locus ID: 6738
• UniProt ID: P10155
• Cytogenetics: 1q31.2
• Protein Families: Transcription Factors
• Protein Pathways: Systemic lupus erythematosus
• MW: 60.7 kDa
• Summary: RNA-binding protein that binds to misfolded non-coding RNAs, pre-5S rRNA, and several small cytoplasmic RNA molecules known as Y RNAs. May stabilize some of these RNAs and protect them from degradation (PubMed:18056422). Binds to endogenous Alu retroelements which are induced by type I interferon and stimulate porinflammaotry cytokine secretion. Regulates the expression of Alu retroelements as well as inflammatory genes (PubMed:26382853).[UniProtKB/Swiss-Prot Function]