HACE1 (NM_020771) Human Tagged ORF Clone Lentiviral Particle

SKU RC205602L4V

Lenti ORF particles, HACE1 (mGFP-tagged) - Human HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 (HACE1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: HACE1
• Synonyms: SPPRS
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205602).
• ACCN: NM_020771
• ORF Size: 2727 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_020771.3
• RefSeq Size: 4576 bp
• RefSeq ORF: 2730 bp
• Locus ID: 57531
• UniProt ID: Q8IYU2
• Cytogenetics: 6q16.3
• Protein Families: Druggable Genome
• MW: 102.2 kDa
• Summary: This gene encodes a HECT domain and ankyrin repeat-containing ubiquitin ligase. The encoded protein is involved in specific tagging of target proteins, leading to their subcellular localization or proteasomal degradation. The protein is a potential tumor suppressor and is involved in the pathophysiology of several tumors, including Wilm's tumor. [provided by RefSeq, Mar 2016]