USP12 (NM_182488) Human Tagged ORF Clone Lentiviral Particle

SKU RC205355L2V

Lenti ORF particles, USP12 (mGFP-tagged) - Human ubiquitin specific peptidase 12 (USP12), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: USP12
• Synonyms: UBH1; USP12L1
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC205355).
• ACCN: NM_182488
• ORF Size: 1110 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_182488.1
• RefSeq Size: 4503 bp
• RefSeq ORF: 1113 bp
• Locus ID: 219333
• UniProt ID: O75317
• Cytogenetics: 13q12.13
• Protein Families: Druggable Genome, Protease
• MW: 42.8 kDa
• Summary: Deubiquitinating enzyme. Has almost no deubiquitinating activity by itself and requires the interaction with WDR20 and WDR48 to have a high activity (PubMed:19075014, PubMed:27373336). Not involved in deubiquitination of monoubiquitinated FANCD2 (PubMed:19075014). In complex with WDR48, acts as a potential tumor suppressor by positively regulating PHLPP1 stability (PubMed:24145035).[UniProtKB/Swiss-Prot Function]