Frataxin (FXN) (NM_000144) Human Tagged ORF Clone Lentiviral Particle

SKU RC204880L4V

Lenti ORF particles, FXN (mGFP-tagged) - Human frataxin (FXN), nuclear gene encoding mitochondrial protein, transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Frataxin
• Synonyms: CyaY; FA; FARR; FRDA; X25
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204880).
• ACCN: NM_000144
• ORF Size: 630 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000144.3
• RefSeq Size: 7168 bp
• RefSeq ORF: 633 bp
• Locus ID: 2395
• UniProt ID: Q16595
• Cytogenetics: 9q21.11
• Domains: Frataxin_Cyay
• Protein Families: Druggable Genome
• MW: 23.1 kDa
• Summary: This nuclear gene encodes a mitochondrial protein which belongs to the FRATAXIN family. The protein functions in regulating mitochondrial iron transport and respiration. The expansion of intronic trinucleotide repeat GAA from 8-33 repeats to >90 repeats results in Friedreich ataxia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]