Osteopontin (SPP1) (NM_001040058) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC204803L4V
- LentiORF®
Lenti ORF particles, SPP1 (mGFP-tagged) - Human secreted phosphoprotein 1 (SPP1), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | Osteopontin |
Synonyms | BNSP; BSPI; ETA-1; OPN |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001040058 |
ORF Size | 942 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC204803).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001040058.1 |
RefSeq Size | 1641 bp |
RefSeq ORF | 945 bp |
Locus ID | 6696 |
UniProt ID | P10451 |
Cytogenetics | 4q22.1 |
Protein Families | Druggable Genome, Secreted Protein |
Protein Pathways | ECM-receptor interaction, Focal adhesion, Toll-like receptor signaling pathway |
MW | 35.4 kDa |
Gene Summary | The protein encoded by this gene is involved in the attachment of osteoclasts to the mineralized bone matrix. The encoded protein is secreted and binds hydroxyapatite with high affinity. The osteoclast vitronectin receptor is found in the cell membrane and may be involved in the binding to this protein. This protein is also a cytokine that upregulates expression of interferon-gamma and interleukin-12. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011] |
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