PAH (NM_000277) Human Tagged ORF Clone Lentiviral Particle

SKU RC204694L4V

Lenti ORF particles, PAH (mGFP-tagged) - Human phenylalanine hydroxylase (PAH), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: PAH
• Synonyms: PH; PKU; PKU1
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204694).
• ACCN: NM_000277
• ORF Size: 1356 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000277.1, NP_000268.1
• RefSeq Size: 2680 bp
• RefSeq ORF: 1359 bp
• Locus ID: 5053
• UniProt ID: P00439
• Cytogenetics: 12q23.2
• Domains: ACT, biopterin_H
• Protein Families: Druggable Genome
• Protein Pathways: Metabolic pathways, Phenylalanine, Phenylalanine metabolism, tyrosine and tryptophan biosynthesis
• MW: 51.8 kDa
• Summary: This gene encodes a member of the biopterin-dependent aromatic amino acid hydroxylase protein family. The encoded phenylalanine hydroxylase enzyme hydroxylates phenylalanine to tyrosine and is the rate-limiting step in phenylalanine catabolism. Deficiency of this enzyme activity results in the autosomal recessive disorder phenylketonuria. [provided by RefSeq, Aug 2017]