TCP1 epsilon (CCT5) (NM_012073) Human Tagged ORF Clone Lentiviral Particle

SKU RC204358L4V

Lenti ORF particles, CCT5 (mGFP-tagged) - Human chaperonin containing TCP1, subunit 5 (epsilon) (CCT5), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: TCP1 epsilon
• Synonyms: CCT-epsilon; CCTE; HEL-S-69; PNAS-102; TCP-1-epsilon
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204358).
• ACCN: NM_012073
• ORF Size: 1623 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_012073.3
• RefSeq Size: 3403 bp
• RefSeq ORF: 1626 bp
• Locus ID: 22948
• UniProt ID: P48643
• Cytogenetics: 5p15.2
• Domains: cpn60_TCP1
• Protein Families: Druggable Genome
• MW: 59.7 kDa
• Summary: The protein encoded by this gene is a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Mutations in this gene cause hereditary sensory and autonomic neuropathy with spastic paraplegia (HSNSP). Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 13. [provided by RefSeq, Apr 2015]