ARSA (NM_000487) Human Tagged ORF Clone Lentiviral Particle

SKU RC204319L4V

Lenti ORF particles, ARSA (mGFP-tagged) - Human arylsulfatase A (ARSA), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: ARSA
• Synonyms: ASA; MLD
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204319).
• ACCN: NM_000487
• ORF Size: 1521 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000487.3
• RefSeq Size: 4325 bp
• RefSeq ORF: 1530 bp
• Locus ID: 410
• UniProt ID: P15289
• Cytogenetics: 22q13.33
• Domains: Sulfatase
• Protein Families: Druggable Genome
• Protein Pathways: Lysosome, Sphingolipid metabolism
• MW: 53.6 kDa
• Summary: The protein encoded by this gene hydrolyzes cerebroside sulfate to cerebroside and sulfate. Defects in this gene lead to metachromatic leucodystrophy (MLD), a progressive demyelination disease which results in a variety of neurological symptoms and ultimately death. Alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Dec 2010]