C14orf172 (TRMT61A) (NM_152307) Human Tagged ORF Clone Lentiviral Particle

SKU RC204071L4V

Lenti ORF particles, TRMT61A (mGFP-tagged) - Human tRNA methyltransferase 61 homolog A (S. cerevisiae) (TRMT61A), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: C14orf172
• Synonyms: C14orf172; GCD14; Gcd14p; hTRM61; TRM61
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC204071).
• ACCN: NM_152307
• ORF Size: 867 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_152307.2, NP_689520.2
• RefSeq Size: 3257 bp
• RefSeq ORF: 870 bp
• Locus ID: 115708
• UniProt ID: Q96FX7
• Cytogenetics: 14q32.33
• Protein Families: Druggable Genome
• MW: 31.4 kDa
• Summary: Catalytic subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA (PubMed:16043508). Catalytic subunit of mRNA N(1)-methyltransferase complex, which mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries (PubMed:29107537, PubMed:29072297).[UniProtKB/Swiss-Prot Function]