TM9SF4 (NM_014742) Human Tagged ORF Clone Lentiviral Particle

SKU RC203648L2V

Lenti ORF particles, TM9SF4 (mGFP-tagged) - Human transmembrane 9 superfamily protein member 4 (TM9SF4), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: TM9SF4
• Synonyms: dJ836N17.2
• Vector: pLenti-C-mGFP
• Mammalian Cell Selection: None
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC203648).
• ACCN: NM_014742
• ORF Size: 1875 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_014742.3, NP_055557.1
• RefSeq Size: 3996 bp
• RefSeq ORF: 1929 bp
• Locus ID: 9777
• UniProt ID: Q92544
• Cytogenetics: 20q11.21
• Domains: EMP70
• Protein Families: Transmembrane
• MW: 72.54 kDa
• Summary: Associates with proteins harboring glycine-rich transmembrane domains and ensures their efficient localization to the cell surface (PubMed:25999474). Regulates the assembly and activity of V-ATPase in colon cancer cells via its interaction with V-type proton ATPase subunit H (ATP6V1H) and contributes to V-ATPase-mediated pH alterations in cancer cells which play an important role in drug resistance and invasiveness of colon cancer cells (PubMed:25659576). Plays an important role in an atypical phagocytic activity of metastatic melanoma cells called cannibalism and is involved in the pH regulation of the intracellular vesicles in tumor cells (PubMed:19893578).[UniProtKB/Swiss-Prot Function]