B MyB (MYBL2) (NM_002466) Human Tagged ORF Clone Lentiviral Particle
SKU
RC203540L4V
Lenti ORF particles, MYBL2 (mGFP-tagged) - Human v-myb myeloblastosis viral oncogene homolog (avian)-like 2 (MYBL2), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | B MyB |
Synonyms | B-MYB; BMYB |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC203540).
|
ACCN | NM_002466 |
ORF Size | 2100 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_002466.2, NP_002457.1 |
RefSeq Size | 2785 bp |
RefSeq ORF | 2103 bp |
Locus ID | 4605 |
UniProt ID | P10244 |
Cytogenetics | 20q13.12 |
Domains | myb_DNA-binding |
Protein Families | Druggable Genome, Stem cell - Pluripotency, Transcription Factors |
MW | 78.8 kDa |
Summary | The protein encoded by this gene, a member of the MYB family of transcription factor genes, is a nuclear protein involved in cell cycle progression. The encoded protein is phosphorylated by cyclin A/cyclin-dependent kinase 2 during the S-phase of the cell cycle and possesses both activator and repressor activities. It has been shown to activate the cell division cycle 2, cyclin D1, and insulin-like growth factor-binding protein 5 genes. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2013] |
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