XLF (NHEJ1) (NM_024782) Human Tagged ORF Clone Lentiviral Particle
SKU
RC203393L4V
Lenti ORF particles, NHEJ1 (mGFP-tagged) - Human nonhomologous end-joining factor 1 (NHEJ1), 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | XLF |
Synonyms | XLF |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC203393).
|
ACCN | NM_024782 |
ORF Size | 897 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_024782.1 |
RefSeq Size | 2119 bp |
RefSeq ORF | 900 bp |
Locus ID | 79840 |
UniProt ID | Q9H9Q4 |
Cytogenetics | 2q35 |
Protein Pathways | Non-homologous end-joining |
MW | 33.3 kDa |
Summary | Double-strand breaks in DNA result from genotoxic stresses and are among the most damaging of DNA lesions. This gene encodes a DNA repair factor essential for the nonhomologous end-joining pathway, which preferentially mediates repair of double-stranded breaks. Mutations in this gene cause different kinds of severe combined immunodeficiency disorders. [provided by RefSeq, Jul 2008] |
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