Lactoferrin (LTF) (NM_002343) Human Tagged ORF Clone Lentiviral Particle
SKU
RC203140L4V
Lenti ORF particles, LTF (mGFP-tagged) - Human lactotransferrin (LTF), transcript variant 1, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | Lactoferrin |
Synonyms | GIG12; HEL110; HLF2; LF |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC203140).
|
ACCN | NM_002343 |
ORF Size | 2133 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_002343.2 |
RefSeq Size | 2390 bp |
RefSeq ORF | 2133 bp |
Locus ID | 4057 |
UniProt ID | P02788 |
Cytogenetics | 3p21.31 |
Domains | TR_FER |
Protein Families | Druggable Genome, Protease, Secreted Protein |
MW | 78.37 kDa |
Summary | This gene is a member of the transferrin family of genes and its protein product is found in the secondary granules of neutrophils. The protein is a major iron-binding protein in milk and body secretions with an antimicrobial activity, making it an important component of the non-specific immune system. The protein demonstrates a broad spectrum of properties, including regulation of iron homeostasis, host defense against a broad range of microbial infections, anti-inflammatory activity, regulation of cellular growth and differentiation and protection against cancer development and metastasis. Antimicrobial, antiviral, antifungal and antiparasitic activity has been found for this protein and its peptides. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2014] |
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