Serum Amyloid P (APCS) (NM_001639) Human Tagged ORF Clone Lentiviral Particle

SKU RC202802L4V

Lenti ORF particles, APCS (mGFP-tagged) - Human amyloid P component, serum (APCS), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Serum Amyloid P
• Synonyms: HEL-S-92n; PTX2; SAP
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202802).
• ACCN: NM_001639
• ORF Size: 669 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_001639.2, NP_001630.1
• RefSeq Size: 960 bp
• RefSeq ORF: 672 bp
• Locus ID: 325
• UniProt ID: P02743
• Cytogenetics: 1q23.2
• Domains: PTX
• Protein Families: Druggable Genome, Secreted Protein
• MW: 25.4 kDa
• Summary: The protein encoded by this gene is a glycoprotein, belonging to the pentraxin family of proteins, which has a characteristic pentameric organization. These family members have considerable sequence homology which is thought to be the result of gene duplication. The binding of the encoded protein to proteins in the pathological amyloid cross-beta fold suggests its possible role as a chaperone. This protein is also thought to control the degradation of chromatin. It has been demonstrated that this protein binds to apoptotic cells at an early stage, which raises the possibility that it is involved in dealing with apoptotic cells in vivo. [provided by RefSeq, Sep 2008]