TIMP3 (NM_000362) Human Tagged ORF Clone Lentiviral Particle

SKU RC202600L4V

Lenti ORF particles, TIMP3 (mGFP-tagged) - Human TIMP metallopeptidase inhibitor 3 (TIMP3), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: TIMP3
• Synonyms: HSMRK222; K222; K222TA2; SFD
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202600).
• ACCN: NM_000362
• ORF Size: 633 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_000362.4
• RefSeq Size: 5496 bp
• RefSeq ORF: 636 bp
• Locus ID: 7078
• UniProt ID: P35625
• Cytogenetics: 22q12.3
• Domains: NTR
• Protein Families: Druggable Genome, Secreted Protein
• MW: 24.1 kDa
• Summary: This gene belongs to the TIMP gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of the extracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy. [provided by RefSeq, Jul 2008]