SPG3A (ATL1) (NM_015915) Human Tagged ORF Clone Lentiviral Particle

SKU RC202310L4V

Lenti ORF particles, ATL1 (mGFP-tagged)-Human atlastin GTPase 1 (ATL1), transcript variant 1, 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: SPG3A
• Synonyms: AD-FSP; atlastin1; FSP1; GBP3; HSN1D; SPG3; SPG3A
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202310).
• ACCN: NM_015915
• ORF Size: 1674 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_015915.3
• RefSeq Size: 2271 bp
• RefSeq ORF: 1677 bp
• Locus ID: 51062
• UniProt ID: Q8WXF7
• Cytogenetics: 14q22.1
• Protein Families: Druggable Genome, Transmembrane
• MW: 63.4 kDa
• Summary: The protein encoded by this gene is a GTPase and a Golgi body transmembrane protein. The encoded protein can form a homotetramer and has been shown to interact with spastin and with mitogen-activated protein kinase kinase kinase kinase 4. This protein may be involved in axonal maintenance as evidenced by the fact that defects in this gene are a cause of spastic paraplegia type 3. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]