MYD88 (NM_002468) Human Tagged ORF Clone Lentiviral Particle

SKU RC202253L4V

Lenti ORF particles, MYD88 (mGFP-tagged) - Human myeloid differentiation primary response gene (88) (MYD88), transcript variant 2, 200ul, >10^7 TU/mL

Product Data

• Tag: mGFP
• Target Symbol: MYD88
• Synonyms: IMD68; MYD88D
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202253).
• ACCN: NM_002468
• ORF Size: 888 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_002468.2
• RefSeq Size: 2862 bp
• RefSeq ORF: 891 bp
• Locus ID: 4615
• UniProt ID: Q99836
• Cytogenetics: 3p22.2
• Domains: DEATH, TIR
• Protein Families: Druggable Genome
• Protein Pathways: Apoptosis, Toll-like receptor signaling pathway
• MW: 33.2 kDa
• Summary: This gene encodes a cytosolic adapter protein that plays a central role in the innate and adaptive immune response. This protein functions as an essential signal transducer in the interleukin-1 and Toll-like receptor signaling pathways. These pathways regulate that activation of numerous proinflammatory genes. The encoded protein consists of an N-terminal death domain and a C-terminal Toll-interleukin1 receptor domain. Patients with defects in this gene have an increased susceptibility to pyogenic bacterial infections. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Feb 2010]