GTF2IRD1 (NM_016328) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC202128L4V
- LentiORF®
Lenti ORF particles, GTF2IRD1 (mGFP-tagged) - Human GTF2I repeat domain containing 1 (GTF2IRD1), transcript variant 1, 200ul, >10^7 TU/mL
Lentiviral Particles: DDK DDK w/ Puro mGFP
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Specifications
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
Tag | mGFP |
Symbol | GTF2IRD1 |
Synonyms | BEN; CREAM1; GTF3; hMusTRD1alpha1; MUSTRD1; RBAP2; WBS; WBSCR11; WBSCR12 |
Mammalian Cell Selection | Puromycin |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_016328 |
ORF Size | 2877 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC202128).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_016328.1 |
RefSeq Size | 3471 bp |
RefSeq ORF | 2880 bp |
Locus ID | 9569 |
UniProt ID | Q9UHL9 |
Cytogenetics | 7q11.23 |
Domains | GTF2I |
Protein Families | Druggable Genome, Transcription Factors |
Protein Pathways | Basal transcription factors |
MW | 106 kDa |
Gene Summary | The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2010] |
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