RAIDD (CRADD) (NM_003805) Human Tagged ORF Clone Lentiviral Particle

SKU RC202050L4V

Lenti ORF particles, CRADD (mGFP-tagged) - Human CASP2 and RIPK1 domain containing adaptor with death domain (CRADD), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: RAIDD
• Synonyms: MRT34; RAIDD
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC202050).
• ACCN: NM_003805
• ORF Size: 597 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_003805.3
• RefSeq Size: 1201 bp
• RefSeq ORF: 600 bp
• Locus ID: 8738
• UniProt ID: P78560
• Cytogenetics: 12q22
• Domains: CARD, DEATH
• Protein Families: Druggable Genome
• MW: 22.7 kDa
• Summary: This gene encodes a protein containing a death domain (DD) motif. This protein recruits caspase 2/ICH1 to the cell death signal transduction complex, which includes tumor necrosis factor receptor 1 (TNFR1A) and RIPK1/RIP kinase, and acts in promoting apoptosis. A mutation in this gene was associated with cognitive disability. A related pseudogene is found on chromosome 3. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2016]