Josephin 1 (JOSD1) (NM_014876) Human Tagged ORF Clone Lentiviral Particle

SKU RC201968L4V

Lenti ORF particles, JOSD1 (mGFP-tagged) - Human Josephin domain containing 1 (JOSD1), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Josephin 1
• Synonyms: dJ508I15.2
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC201968).
• ACCN: NM_014876
• ORF Size: 606 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_014876.3
• RefSeq Size: 3435 bp
• RefSeq ORF: 609 bp
• Locus ID: 9929
• UniProt ID: Q15040
• Cytogenetics: 22q13.1
• Domains: Josephin
• Protein Families: Druggable Genome
• MW: 23.2 kDa
• Summary: Deubiquitinates monoubiquitinated probes (in vitro). When ubiquitinated, cleaves 'Lys-63'-linked and 'Lys-48'-linked poly-ubiquitin chains (in vitro), hence may act as a deubiquitinating enzyme. May increase macropinocytosis and suppress clathrin- and caveolae-mediated endocytosis. May enhance membrane dynamics and cell motility independently of its catalytic activity.[UniProtKB/Swiss-Prot Function]