GCP4 (TUBGCP4) (NM_014444) Human Tagged ORF Clone Lentiviral Particle

SKU RC200872L4V

Lenti ORF particles, TUBGCP4 (mGFP-tagged) - Human tubulin, gamma complex associated protein 4 (TUBGCP4), 200ul, >10^7 TU/mL

Product Data

• Type: Human Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: GCP4
• Synonyms: 76P; GCP-4; GCP4; Grip76; MCCRP3
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(RC200872).
• ACCN: NM_014444
• ORF Size: 1998 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_014444.2
• RefSeq Size: 4178 bp
• RefSeq ORF: 2001 bp
• Locus ID: 27229
• UniProt ID: Q9UGJ1
• Cytogenetics: 15q15.3
• Domains: Spc97_Spc98
• MW: 76 kDa
• Summary: This gene encodes a component of the gamma-tubulin ring complex, which is required for microtubule nucleation. In mammalian cells, the protein localizes to centrosomes in association with gamma-tubulin. Crystal structure analysis revealed a structure composed of five helical bundles arranged around conserved hydrophobic cores. An exposed surface area located in the C-terminal domain is essential and sufficient for direct binding to gamma-tubulin. Mutations in this gene that alter microtubule organization are associated with microcephaly and chorioretinopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, May 2015]