RAB7L1 (RAB29) (NM_003929) Human Tagged ORF Clone Lentiviral Particle
SKU
RC200431L4V
Lenti ORF particles, RAB29 (mGFP-tagged) - Human RAB7, member RAS oncogene family-like 1 (RAB7L1), transcript variant 1, 200ul, >10^7 TU/mL
Product Data | |
Type | Human Tagged ORF Clone Lentiviral Particle |
---|---|
Tag | mGFP |
Target Symbol | RAB7L1 |
Synonyms | RAB7L; RAB7L1 |
Vector | pLenti-C-mGFP-P2A-Puro |
Mammalian Cell Selection | Puromycin |
Sequence Data |
ORF Nucleotide Sequence
The ORF insert of this clone is exactly the same as(RC200431).
|
ACCN | NM_003929 |
ORF Size | 609 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Shipping | Dry Ice |
Reference Data | |
RefSeq | NM_003929.1 |
RefSeq Size | 3324 bp |
RefSeq ORF | 612 bp |
Locus ID | 8934 |
UniProt ID | O14966 |
Cytogenetics | 1q32.1 |
Domains | RAB, RAN, ras, RAS, RHO |
Protein Families | Druggable Genome |
MW | 23.2 kDa |
Summary | Rab GTPase key regulator in vesicle trafficking. Essential for maintaining the integrity of the endosome-trans-Golgi network structure. Together with LRRK2, plays a role in the retrograde trafficking pathway for recycling proteins, such as mannose 6 phosphate receptor (M6PR), between lysosomes and the Golgi apparatus in a retromer-dependent manner. Regulates neuronal process morphology in the intact central nervous system (CNS). May play a role in the formation of typhoid toxin transport intermediates during Salmonella enterica serovar Typhi (S.Typhi) epithelial cell infection.[UniProtKB/Swiss-Prot Function] |
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