Prf1 (NM_011073) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR227213L4V

Lenti ORF particles, Prf1 (GFP-tagged) - Mouse perforin 1 (pore forming protein) (Prf1), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Prf1
• Synonyms: Pfn; Pfp; Prf-1
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR227213).
• ACCN: NM_011073
• ORF Size: 1662 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_011073.3, NP_035203.3
• RefSeq Size: 2054 bp
• RefSeq ORF: 1665 bp
• Locus ID: 18646
• UniProt ID: P10820
• Cytogenetics: 10 32.18 cM
• Summary: Plays a key role in secretory granule-dependent cell death, and in defense against virus-infected or neoplastic cells. Can insert into the membrane of target cells in its calcium-bound form, oligomerize and form large pores. Promotes cytolysis and apoptosis of target cells by facilitating the uptake of cytotoxic granzymes.[UniProtKB/Swiss-Prot Function]