Ptpn1 (NM_011201) Mouse Tagged ORF Clone Lentiviral Particle

SKU MR227012L4V

Lenti ORF particles, Ptpn1 (GFP-tagged) - Mouse protein tyrosine phosphatase, non-receptor type 1 (Ptpn1), 200ul, >10^7 TU/mL

Product Data

• Type: Mouse Tagged ORF Clone Lentiviral Particle
• Tag: mGFP
• Target Symbol: Ptpn1
• Synonyms: PTP-1B; PTP-HA2; PTP1B
• Vector: pLenti-C-mGFP-P2A-Puro
• Mammalian Cell Selection: Puromycin
• Sequence Data:
  ORF Nucleotide Sequence

  The ORF insert of this clone is exactly the same as(MR227012).
• ACCN: NM_011201
• ORF Size: 1296 bp
• OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
• OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
• Shipping: Dry Ice

Reference Data

• RefSeq: NM_011201.3, NP_035331.3
• RefSeq Size: 4213 bp
• RefSeq ORF: 1299 bp
• Locus ID: 19246
• UniProt ID: P35821
• Cytogenetics: 2 H3
• Summary: Tyrosine-protein phosphatase which acts as a regulator of endoplasmic reticulum unfolded protein response. Mediates dephosphorylation of EIF2AK3/PERK; inactivating the protein kinase activity of EIF2AK3/PERK. May play an important role in CKII- and p60c-src-induced signal transduction cascades. May regulate the EFNA5-EPHA3 signaling pathway which modulates cell reorganization and cell-cell repulsion. May also regulate the hepatocyte growth factor receptor signaling pathway through dephosphorylation of MET (By similarity).[UniProtKB/Swiss-Prot Function]